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  • Company overview
  • Technology - The drug development process at IRP, The Drug Evaluation Process, Model systems
  • Contact us
  • A comprehensive process for evaluation of respiratory drugs
    975 Cornforth Drive
    Kent Science Park
    Sittingbourne, Kent ME9 8PX
    T 01795 437426
    F 01795 423440
    E info@irpharma.co.uk
    National Heart & Lung Institute
    Sir Alexander Fleming Building
    Imperial College, London SW7 2AZ
    T 01795 437426
    F 01795 423440
    E info@irpharma.co.uk

    Technology Overview - The drug development process at IRP

    IRP can provide a range of models and tests that together provide a comprehensive process for evaluation of respiratory drugs. The process essentially comprises four key stages, which represents current best practise in respiratory drug evaluation and encompasses:

    • target validation
    • in vitro profiling
    • in vivo profiling
    • pharmacological assessment of key biomarkers

    In addition to methods for investigating parameters within normal tissue, IR Pharma has developed respiratory disease models tailored to evaluate drug efficacy in;

    • Asthma
    • COPD

    We believe this combination of assays and models provides a front line capability for those companies wishing to gain insight into effects and efficacy of drug candidates at the pre-clinical stage.